Local and regional manufacturing


Local and regional man­u­fac­tur­ing broadly refers to the man­u­fac­ture of health prod­ucts at the local or regional lev­els, par­tic­u­larly in low- and mid­dle-income coun­tries. Health prod­ucts encom­pass a wide range of health prod­ucts includ­ing small-mol­e­cule drugs, bio­log­ics, vac­cines, diag­nos­tics, and cell- and gene-ther­a­pies. Enhanc­ing local and regional man­u­fac­tur­ing capac­ity is increas­ingly being rec­og­nized as nec­es­sary to ensure equi­table access to health prod­ucts. Enhanc­ing local and regional man­u­fac­tur­ing can also increase health sys­tem resilience and reduce depen­dence from for­eign indus­try and polit­i­cal pow­ers. Local capa­bil­i­ties can be enhanced with inter­ven­tions that include pub­lic, pri­vate, and phil­an­thropic man­u­fac­tur­ers.

Strength­en­ing the capac­ity to man­u­fac­ture health prod­ucts locally or region­ally often requires build­ing phys­i­cal infra­struc­tures, increas­ing tech­ni­cal skills, improv­ing reg­u­la­tory envi­ron­ments, pub­lic pro­cure­ment, non-exclu­sive intel­lec­tual prop­erty licens­ing, and open shar­ing of knowl­edge. The occur­rence of these types of inter­ven­tions is dri­ven by legal and pol­icy frame­works, as well as polit­i­cal will for instance to increase domes­tic invest­ments and other national efforts. Long term and sus­tain­able local and regional man­u­fac­tur­ing capa­bil­ity can be cre­ated by strength­en­ing research and devel­op­ment capa­bil­i­ties.

Sev­eral ini­tia­tives are under­way to strengthen local and regional capac­i­ties to man­u­fac­ture health prod­ucts, many of them moti­vated by global inequitable dis­tri­bu­tion dur­ing the COVID-19 pan­demic. As reflected in the Lan­guage Com­pendium, sev­eral inter­na­tional prece­dents have called for sup­port to these and other ini­tia­tives to strengthen local and regional man­u­fac­tur­ing.


2022 Resolution on elevating pandemic prevention, preparedness and response to the highest level of political leadership

2022 HRC Res­o­lu­tion on access to medicines, vaccines and other health products

2021 Resolution on science, technology and innovation for sustainable development

2020 Resolution on comprehensive and coordinated response to the coronavirus disease (COVID-19) pandemic