Combination prevention


Com­bi­na­tion pre­ven­tion are rights-, evi­dence-, and com­mu­nity-based pro­grams that pro­mote a com­bi­na­tion of bio­med­ical, behav­ioral, and struc­tural inter­ven­tions designed to meet the HIV pre­ven­tion needs of spe­cific peo­ple and com­mu­ni­ties. Com­bi­na­tion pre­ven­tion has the poten­tial to reduce HIV infec­tions through activ­i­ties with a greater sus­tained impact. Exam­ples of com­bi­na­tion pre­ven­tion pro­grams include the focus on edu­cat­ing and train­ing vul­ner­a­ble groups to coun­sel and advo­cate for pol­icy change while at the same time ensur­ing inte­grated pre­ven­ta­tive health­care ser­vices and prod­ucts. Com­bi­na­tion pre­ven­tion requires evi­dence-based, stake­holder dri­ven, rights-based and inclu­sive pro­grammes with account­abil­ity mech­a­nisms. While applic­a­ble for HIV, com­bi­na­tion pre­ven­tion approaches can also be used for other dis­eases.

Inter­na­tion­ally agreed com­mit­ments reflected in the Lan­guage Com­pendium have rec­og­nized the need to increase national lead­er­ship, resource allo­ca­tion, and other mea­sures for proven HIV com­bi­na­tion pre­ven­tion, “includ­ing con­dom pro­mo­tion and dis­tri­bu­tion, pre-expo­sure pro­phy­laxis, post-expo­sure pro­phy­laxis, vol­un­tary male med­ical cir­cum­ci­sion, harm reduc­tion, in accor­dance with national leg­is­la­tion, sex­ual and repro­duc­tive health-care ser­vices, includ­ing screen­ing and treat­ment of sex­u­ally trans­mit­ted infec­tions, enabling legal and pol­icy envi­ron­ments, full access to com­pre­hen­sive infor­ma­tion and edu­ca­tion, in and out of school.”

Prece­dents rec­og­niz­ing the need to tai­lor HIV com­bi­na­tion pre­ven­tion approaches to meet the diverse needs of key pop­u­la­tions have also been adopted, as reflected in the Lan­guage Com­pendium. Inter­na­tional com­mit­ments to ensure by 2025 that 95 per­cent of peo­ple at risk of HIV infec­tion have access to and use appro­pri­ate, pri­or­i­tized, per­son-cen­tered, and effec­tive com­bi­na­tion pre­ven­tion options also exists.


2021 Political declaration on HIV and AIDS

2019 Political declaration of the HLM on UHC

2017 Resolution on international cooperation to address and counter the world drug problem

2016 Outcome Document of the Session on the World Drug Problem

2016 Resolution on Women, the Girl Child and HIV and AIDS

2016 Political Declaration on HIV and AIDS

2016 Resolution on the girl child


2021 WHO Updated Recommendations on HIV Prevention, EID and ART

2021 WHO Consolidated Guidelines on HIV Prevention, Testing, Treatment, Service Delivery and Monitoring

2020 Evidence Review of the UNAIDS Strategy 2016-2021

2016 Prevention Gap Report

2015 Fast-Tracking Combination Prevention